Myxedema Coma Medscape | cocreatorsinstitute.net

Myxedema coma. J Intensive Care Med. 2007; 224:224-31 ISSN: 0885-0666 Kwaku MP; Burman KD. Untreated or unrecognized hypothyroidism may progress to severe decompensated hypothyroidism or myxedema coma. Relatively few cases are reported in the literature since the first case was apparently reported from the St. Thomas Hospital in London in 1879. Myxedema coma is the term given to the most severe presentation of profound hypothyroidism and is often fatal in spite of therapy. Decompensation of the hypothyroid patient into a coma may be precipitated by a number of drugs, systemic illnesses eg, pneumonia, and other causes. Most authorities recommend treatment with intravenous levothyroxine T4 as opposed to intravenous liothyronine T3. Hydrocortisone should be administered until coexisting adrenal insufficiency is ruled out. Family physicians are in an important position to prevent myxedema coma by maintaining a high level of suspicion for hypothyroidism. Hypothyroidism is a frequently diagnosed and simply treated disease. If not recognised, however, in time it may develop into the most severe manifestation of hypothyroidism known as myxedema coma. The term "myxedema coma" is generally seen as misleading since most patients do not initially present in a coma. Myxedema coma is a medical emergency that requires immediate attention. If the diagnosis is suspected, immediate management is necessary before confirming the diagnosis due to the high associated mortality rate. Patients with myxedema coma should be managed in an intensive care unit with continuous cardiac monitoring.

Myxedema coma, or critical hypothyroidism, occurs most often in patients with long-standing, preexisting hypothyroidism. Hypothyroidism is 4 times more common in women than in men, and 80% of cases of myxedema coma occur in females. It occurs almost exclusively in persons 60 years or older. Early recognition and therapy of myxedema coma are essential. Treatment should be initiated on the basis of clinical suspicion without waiting for laboratory results. Important clues to the possible presence of myxedema coma in a poorly responsive patient are the presence of a thyroidectomy scar or a history of radioiodine therapy or. Myxedema coma or myxedema crisis is a life-threatening complication of hypothyroidism. Some symptoms of myxedema coma include fatigue, lethargy, depression, dry skin, and weight gain. Mild myxedema coma usually is treated by a general practitioner or internist while moderate to severe myxedema coma is treated and managed by an endocrinologist. Myxedema Coma Overview. The thyroid gland, located at the front part of the neck, is responsible for making substances called thyroid hormones that are important for all body cells to work.

Medscape - Hypothyroidism-specific dosing for Synthroid, Levoxyl levothyroxine, frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy &. El coma mixedematoso es la manifestación severa del hipotiroidismo, una condición que ocurre cuando el cuerpo carece de suficiente hormona tiroidea. Los pacientes con hipotiroidismo suelen padecer de alteraciones fisiológicas como consecuencia del cuerpo tratando de.

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